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vcfanno for Mac

Annotate a VCF with other VCFs/BEDs/tabixed files

Quick answer: vcfanno is a command-line tool for macOS. Install it with brew install vcfanno. It is distributed under the MIT licence.

What vcfanno is

vcfanno is a command-line tool for macOS: annotate a VCF with other VCFs/BEDs/tabixed files.

It is distributed as a Homebrew formula, which builds or pours a binary and puts it on your PATH. It is distributed under the MIT licence.

How to install vcfanno

  1. Open Terminal (press ⌘ + Space and type “Terminal”).
  2. If Homebrew is not installed yet, run the installer below once.
  3. Run brew install vcfanno.

Homebrew installer, if you need it:

Prefer a graphical installer? Download it from the official site. MacPicks never hosts or mirrors binaries — the Homebrew command always pulls from the vendor's own release.

Similar apps in Command-Line Tools

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gffcompareCompare, merge and annotate GFF/GTF transcript filesCLIOpen source1/moslivarFilter and annotate genetic variants with expressions, for trios and cohortsCLIOpen source6/movcflibC++ library and cmdline tools for parsing and manipulating VCF filesCLIOpen source10/movcfexpressFilter and format VCF/BCF files with Lua expressionsCLIOpen source12/movcftoolsTools for working with VCF filesCLIOpen source17/mosomalierRelatedness, QC and ancestry checks from BAM/CRAM/VCFCLIOpen source19/mo

Frequently asked questions

How do I install vcfanno on Mac?

Run brew install vcfanno in Terminal. This requires Homebrew; if you do not have it, install it first with the command below.

Is vcfanno open source?

Yes — Homebrew distributes it under the MIT licence.

Does vcfanno run on Apple silicon?

Homebrew publishes this formula for macOS. If upstream does not ship an Apple silicon build, Rosetta 2 handles the Intel binary.

How popular is vcfanno?

Homebrew does not publish a 30-day install count for this package, which usually means it is installed directly rather than through the analytics-reporting path.

What version of vcfanno is current?

The latest packaged version is 0.3.9.